Tsanangudzo Pfupi
Nhamba yeCAS: 7177-48-2
Molecular formula: C16H25N3O7S
molecular uremu:403.45
Kemikari chimiro:
| Basic Information | |
| Product name | Ampicillin |
| Giredhi | Pharmaceutical Grade |
| Chitarisiko | Ichena kana inenge yakachena, crystalline powder |
| Assay | |
| Sherufu hupenyu | 2 Makore |
| Packing | 25kg / chigubhu |
| Condition | zvakachengetwa munzvimbo inotonhorera uye yakaoma |
Tsanangudzo
Seboka repenicillin re beta-lactam mishonga inorwisa mabhakitiriya, Ampicillin ndiyo yekutanga yakakura-spectrum penicillin, ine in vitro chiitiko kurwisa Gram-positive uye Gram-negative aerobic uye anaerobic mabhakitiriya, anowanzoshandiswa kudzivirira nekurapa hutachiona hwehutachiona hwekufema, weti. turakiti, nzeve yepakati, sinuses, dumbu uye ura, dundira, uye itsvo, etc. zvichikonzerwa nehutachiona hwehutachiona. Inoshandiswawo kurapa gonorrhea isina kuoma, meningitis, endocarditis salmonellosis, uye zvimwe zvirwere zvakakomba kuburikidza nekupiwa nemuromo, intramuscular jekiseni kana kuti intravenous infusion. Kufanana nemishonga inorwisa mabhakitiriya, haibatsiri pakurapa kwehutachiona hwehutachiona.
Ampicillin inoshanda nekuuraya mabhakitiriya kana kudzivirira kukura kwawo. Mushure mekupinda mabhakitiriya eGram-positive uye Gram-negative, inoshanda sechinhu chisingachinjiki inhibitor ye enzyme transpeptidase inodiwa nebhakitiriya kuti iite rusvingo rwesero, izvo zvinoguma nekudziviswa kwesero rusvingo synthesis uye pakupedzisira zvinotungamirira kumasero lysis.
Antimicrobial basa
Ampicillin haina kushanda zvishoma pane benzylpenicillin ichirwisa mabhakitiriya mazhinji eGram-positive asi inoshanda zvakanyanya pakurwisa E. faecalis. MRSA nemhando dzeStr. pneumoniae ine kuderedzwa kubatwa nebenzylpenicillin inoshingirira. Vazhinji boka D streptococci, anaerobic Gram-positive cocci uye bacilli, kusanganisira L. monocytogenes, Actinomyces spp. uye Arachnia spp., inotapukirwa. Mycobacteria uye nocardia inopikisa.
Ampicillin ine basa rakafanana nebenzylpenicillin kurwisa N. gonorrhoeae, N. meningitidis neMor. catarrhalis. Inoita 2-8 nguva yakawanda kupfuura benzylpenicillin inorwisana neH. influenzae uye yakawanda Enterobacteriaceae, asi β-lactamase-inobudisa marudzi inopesana. Pseudomonas spp. inoshingirira, asi Bordetella, Brucella, Legionella uye Campylobacter spp. kazhinji vanobatwa. Mamwe maGram-negative anaerobes akadai sePrevotella melaninogenica uye Fusobacterium spp. zvinotapukira, asi B. fragilis inodzivirira, sezvakaita mycoplasmas uye rickettsiae.
Chiito chinopesana nekirasi A β-lactamase-inobudisa marudzi e staphylococci, gonococci, H. influenzae, Mor. catarrhalis, imwe Enterobacteriaceae uye B. fragilis inowedzerwa nekuvapo kwe-β-lactamase inhibitors, kunyanya clavulanic acid.
Basa rayo rebhaktericidal rakafanana nebenzylpenicillin. Bactericidal synergy inowanikwa neaminoglycosides kurwisa E. faecalis uye akawanda enterobacteria, uye ne mecillinam kurwisa huwandu hweampicillin-resistant enterobacteria.
