Tsanangudzo Pfupi
CAS nhamba: 50-78-2
Molecular formula:C9H8O4
molecular uremu:180.16
Kemikari chimiro:
| Basic Information | |
| Mamwe mazita | Acetylsalicylic acid |
| Product name | Aspirin |
| Giredhi | Pharma Giredhi / Feed Giredhi |
| Chitarisiko | White crystalline powder |
| Assay | 99% |
| Sherufu hupenyu | 2 years |
| Hunhu | Zvishoma kunyungudika mumvura, soluble mu ethanol, ethyl ether, chloroform, sodium hydroxide solution uye sodium carbonate solution. |
| Storage | Ramba uri munzvimbo inotonhorera yakaoma |
Chigadzirwa tsananguro
Aspirin, inozivikanwawo seacetylsalicylic acid (ASA), mushonga unoshandiswa kuderedza marwadzo, fivha, kana kuzvimba.Specific inflammatory conditions iyo aspirin inoshandiswa kurapa inosanganisira chirwere cheKawasaki, pericarditis, uye rheumatic fever. Aspirin ndiwo mushonga unoshandiswa zvakanyanya pasi rose.
Function
Acetylsalicylic acid ine antipyretic analgesic, anti-inflammatory uye anti-rheumatism effect, ndosaka inowanzoshandiswa kune fivha, musoro, kurwadziwa kwemhasuru, neuralgia, rheumatic fever, acute rheumatic arthritis, gout, nezvimwewo; zvakare ine antiplatelet aggregation athari, uye inogona kushandiswa kudzivirira arterial thrombosis, atherosclerosis, yenguva pfupi cerebral ischemia uye myocardial infarction; uyezve, acetylsalicylic acid zvakare inogona kushandiswa mukurapa biliary turakiti roundworm chirwere uye tsoka yemutambi.
Pharmacological zviito
Acetylsalicylic asidhi ndeimwe yeagarage antipyretic analgesics, pamwe nebasa rekuunganidzwa kweplatelet. Acetylsalicylic acid mumuviri ine hunhu hweantithrombotic, inogona kuderedza kuumbwa kweanovharira magwamba eropa mutsinga dzakatenderedza, uye inhibisa kuburitswa kweplatelet mhinduro uye endogenous ADP, 5-HT, zvichingodaro, nekudaro inhibisa chikamu chechipiri kunze kwekutanga. chikamu cheplatelet aggregation. Iyo nzira yekuita kweacetylsalicylic acid ndeyekugadzira maplatelet cyclooxygenase acetylation, nokudaro ichidzivisa kuumbwa kwering peroxide, uye TXA2 kuumbwa kunoderedzwawo zvakare. Panguva ino gadzira platelet membrane protein acetylation, uye inhibit platelet membrane enzyme, iyo inobatsira kuvharidzira kushanda kweplatelet. Sezvo cyclooxygenase inodzivirirwa, inokanganisa rusvingo rweropa rwakagadzirwa kuva PGI2, iyo platelet TXA2 synthetic enzymes inofanirawo kudziviswa; saka zvaizokanganisa kuumbwa kwezvose zviri zviviri TXA2 nePGI2 kana iri madosi makuru. Inokodzera ischemic heart disease, mushure me percutaneous transluminal coronary angioplasty kana coronary artery bypass grafting, kudzivirira kwenguva pfupi ischemic sitiroko, myocardial infarction uye kuderedza kuitika kwearrhythmia. Acetylsalicylic acid zvakare inogona kushandiswa mukurapa biliary turakiti roundworm chirwere uye tsoka yemutambi.
Application
Ndiyo yekutanga kushandiswa, inonyanya kufarirwa uye yakajairika antipyretic analgesics anti-rheumatism mushonga, ine zvikamu zvepharmacological mhedzisiro se antipyretic-analgesic uye anti-inflammatory, anti-platelet aggregation uye inoshanda nekukurumidza uye zvinobudirira. Overdosage inogona kuongororwa zviri nyore uye kurapwa, ine isingawanzo allergic reactions. Inowanzo shandiswa kutonhora kupisa, kutemwa nemusoro, neuralgia, kurwadza kwemajoini, kurwadziwa kwemhasuru, rheumatic fever, acute wet sex arthritis, rheumatoid arthritis uye kurwadza kwezino, etc. Yakanyorwa muNational Essential Medicine List. Acetylsalicylic acid inoshandawo sepakati pemimwe mishonga.
