Tsanangudzo Pfupi
Nhamba yeCAS:24729-96-2
Molecular formula:C18H34ClN2O8PS
molecular uremu:504.96
Kemikari chimiro:
| Basic Information | |
| Product name | Clindamycin Phosphate |
| Giredhi | Pharma giredhi |
| Chitarisiko | hupfu chena |
| Assay | 95% |
| Sherufu hupenyu | 2 years |
| Packing | 25kg / chigubhu |
| Condition | Yakagadzikana, asi chengetedza inotonhorera. Izvo zvisingaenderani neakasimba oxidizing agents, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B group sodium mavitamini. |
Tsanangudzo
Clindamycin phosphate is ester-soluble ester yesemisynthetic antibiotic inogadzirwa ne7 (S) -chloro-inotsiva ye7 (R) -hydroxyl boka revabereki mushonga, lincomycin. Inobva pa lincomycin (a lincosamide). Iyo ine kunyanya bacteriostatic chiito chinopesana neGram-positive aerobes uye huwandu hwakawanda hweanaerobicbacteria. Mushonga unorwisa mabhakitiriya unoshandiswa mukurapa utachiona. Izvi zvinogona kusanganisira zvirwere zvekufema, septicemia, peritonitis uye zvirwere zvemapfupa. Inoshandiswawo kurapa zvine mwero kusvika kune zvakanyanya acne.
Shandisa
Clindamycin phosphate inoshandiswa pamusoro pega kana pamwe chete nebenzoyl peroxide mukurapa kwekuzvimba acne vulgaris. Mukuyera mabhenefiti angangove eiyo topical clindamycin therapy, mukana weyakakomba yakashata GI mhedzisiro ine chekuita nemushonga inofanirwa kutariswa. Kurapa kweacne vulgaris kunofanirwa kuve kwakasarudzika uye kunowanzo gadziridzwa zvichienderana nemhando dzemaronda emushonga anotungamira uye nemhinduro yekurapa. Topical anti-infectives, kusanganisira clindamycin, kazhinji inoshanda mukurapa kwehunyoro kusvika pakati nepakati. Zvisinei, kushandiswa kwema-topical anti-infectives se monotherapy kunogona kutungamirira kukudzivirira kwebhakitiriya; kuramba uku kunoenderana nekuderera kwehutano hwekurapa.Topical clindamycin inonyanya kubatsira kana ikashandiswa nebenzoyl peroxide kana topical retinoids. Mhedzisiro yezvidzidzo zvekiriniki inoratidza kuti kurapa kwakasanganiswa kunoguma nekudzikiswa kwehuwandu hwemaronda e50-70%.
Clindamycin 2-phosphate imunyu weclincamycin, semi-synthetic lincosamide. Munyu unogadzirwa nekusarudza phosphorylation ye2-hydroxy moiety yeshuga ye clindamycin. Kuunzwa kwephosphate kunopa kunyungudika kuri nani kwemajekiseni ekugadzira. Kufanana nedzimwe nhengo dzemhuri ye lincosamide, clindamycin 2-phosphate mushonga unorwisa mabhakitiriya weanaerobic uye protozoans wakakura. Clindamycin inoshanda nekusunga kune 23S ribosomal subunit, ichivharira mapuroteni synthesis.
