Basic Information | |
Product name | Folate Mahwendefa |
Mamwe mazita | Folic Acid Tablet, Activated Folate Tablet, Active Folic Acid Tablet, zvichingodaro. |
Giredhi | Chikafu chegiredhi |
Chitarisiko | Sezvinodiwa nevatengi Round, Oval, Oblong, Triangle, Dhaimondi uye mamwe maumbirwo akakosha ese aripo. |
Sherufu hupenyu | 2-3 makore, zvichienderana nemamiriro echitoro |
Packing | Kuwanda, mabhodhoro, blister mapaketi kana zvinodiwa nevatengi |
Condition | Chengetedza mumidziyo yakasimba, yakadzivirirwa kubva kuchiedza. |
Tsanangudzo
Migumisiro ye folic acid pane zvipenyu inonyanya kuratidzwa mune zvinotevera: kubatanidzwa mumetabolism ye genetic material uye mapuroteni; kukanganisa kubereka kwemhuka; kukanganisa kugadzirwa kwepancreas yemhuka; kukurudzira kukura kwemhuka; uye kuvandudza kudzivirira kwemuviri.
Methyltetrahydrofolate inowanzoreva 5-methyltetrahydrofolate, iyo ine basa rekupa muviri muviri uye kuwedzera folic acid. 5-Methyltetrahydrofolate chinhu chine mabasa anoshanda anoshandurwa kubva kufolic acid kuburikidza neakatevedzana maitiro ebiochemical mumuviri wemunhu. Inogona kushandiswa zvakananga nemuviri munzira dzakasiyana siyana dzemetabolism kuchengetedza kushanda kwakajairwa kwemuviri, nekudaro kuita basa mukusimbisa muviri.
Function
Folic acid imhando yevhithamini B, inozivikanwawo septeroylglutamic acid. 5-methyltetrahydrofolate ndiyo nhanho yekupedzisira mune metabolism uye shanduko ye folic acid mumuviri. Nekuda kwebasa rayo rinoshanda, inonziwo inoshanda. Folic acid inhengo ye metabolic ye folic acid iri mumuviri.
Nekuti iyo molecular chimiro che5-methyltetrahydrofolate inogona kunyudzwa zvakananga nemuviri pasina kuita yakaoma metabolic shanduko maitiro, inowanikwa zvakanyanya mumasero emuviri. Kuenzaniswa nefolic acid, zviri nyore kuwedzera zvinovaka muviri kumuviri, kunyanya kuvakadzi vanoda kugadzirira kubata pamuviri uye vakadzi vane pamuviri panguva yekuzvitakura.
Folic acid ndeimwe yevhitamini yakakosha pakukura nekuberekana kwemasero emuviri. Kushaikwa kwayo kuchakanganisa zvakajairika physiological zviitiko zvemuviri wemunhu. Mabhuku akawanda akashuma kuti kushaikwa kwefolic acid kwakabatana zvakananga neural tube defects, megaloblastic anemia, cleft lip uye palate, kuora mwoyo, mapundu nezvimwe zvirwere.
Neural tube malformations (NTDs)
Neural tube malformations (NTDs) iboka rezvakaremara zvinokonzerwa nekuvharwa kusina kukwana kweneural tube panguva yekukura kwe embryonic, kusanganisira anencephaly, encephalocele, spina bifida, nezvimwewo, uye ndeimwe yezvinowanzoonekwa neonatal defects. Muna 1991, British Medical Research Council yakasimbisa kekutanga kuti folic acid supplementation isati yasvika uye mushure mekuita pamuviri inogona kudzivirira kuitika kweNTD uye kuderedza chiitiko ne50-70%. Kudzivirirwa kwe folic acid paNTDs kwave kutorwa sechimwe chezvinhu zvinonakidza zvakawanikwa zvekurapa mukupera kwezana ramakore rechi20.
Megaloblastic anemia (MA)
Megaloblastic anemia (MA) imhando yeanemia inokonzerwa nekukanganiswa kweDNA synthesis kunokonzerwa nekushaikwa kwefolic acid kana vhitamini B12. Inowanzoonekwa mucheche uye vakadzi vane pamuviri. Kukura zvakanaka kwe "fetus" kunoda huwandu hwakawanda hwefolic acid reserves mumuviri waamai. Kana folic acid yakachengetwa yakapera panguva yekusununguka kana kutanga mushure mekusununguka, megaloblastic anemia inoitika mumwana uye amai. Mushure mekuwedzera ne folic acid, chirwere chinogona kukurumidza kupora uye kurapwa.
Folic acid uye muromo wakatsemuka uye mukanwa
Cleft lip and palate (CLP) chimwe chezvakanyanya kuzvarwa hurema hwekuzvarwa. Chikonzero chekutsemuka kwemiromo nemukanwa hazvisati zvanyatsojeka. Folic acid supplementation panguva yekuzvitakura yakaratidza kudzivirira kuberekwa kwevana vane muromo wakatsemuka uye mukanwa.
Zvimwe zvirwere
Kushaikwa kwefolic acid kunogona kukonzera kukuvadza kukuru kumadzimai nevana, sekugara kupfupfudzika, kuberekwa nguva isati yakwana, uremu hwekuzvarwa hushoma, kushaya kudya kwe fetal uye kunonoka kukura. Mabhuku mazhinji anoshuma kuti chirwere cheAlzheimer, kushushikana, uye kusagadzikana kwetsinga muvana vachangozvarwa uye mamwe maronda ehuropi ane hukama zvese zvine chekuita nekushomeka kwefolic acid. Pamusoro pezvo, kushaikwa kwefolic acid kunogona kukonzerawo mapundu (gomarara rechibereko, kenza yebronchi, kenza yesophageal, colorectal cancer, nezvimwewo), chisingaperi atrophic gastritis, colitis, chirwere chemoyo uye chirwere checerebrovascular, pamwe nezvimwe zvirwere senge glossitis uye. kusakura zvakanaka. Vanhu vakuru vasina folic acid uye vanonwa doro rakawandisa vanogona kushandura chimiro chemukati mucosa yavo.
Applications
1. Vakadzi panguva yekugadzirira pamuviri uye pamuviri wepakutanga.
2. Vanhu vane anemia.
3. Vanhu vane homocysteine yakakwirira.