Tsanangudzo Pfupi
Nhamba yeCAS: 1197-18-8
Molecular formula: C8H15NO2
molecular uremu: 157.21
Kemikari chimiro:
| Basic Information | |
| Product name | Tranexamic Acid |
| Giredhi | Cosmetic Giredhi |
| Chitarisiko | Ichena kana inenge yakachena, crystalline powder |
| Assay | 99% |
| Sherufu hupenyu | 2 years |
| Packing | 25kg / chigubhu |
| Chemical Properties | Inonyungudika zvakasununguka mumvura uye mu glacial acetic acid uye inonyungudika zvishoma mu ethanol uye isinganyungudika mu ether. |
Tsanangudzo
Tranexamic acid inotorwa kubva kuaminomethylbenzoic acid, uye rudzi rwemishonga yeantifibrinolytic yekumisa kubuda ropa. Iyo hemostasis mechanism ye tranexamic acid yakafanana neaminocaproic acid uye aminomethylbenzoic acid, asi mhedzisiro yacho yakasimba. Simba racho 7 kusvika ku10 nguva dzeaminocaproic acid, 2 nguva dzeaminomethylbenzoic acid, asi huturu hwakafanana.
Chimiro chemakemikari chetranexamic acid chakafanana ne lysine, kukwikwidza kuvharidzirwa kweplasmin yepakutanga mufibrin adsorption, kudzivirira kushandiswa kwavo, kuchengetedza fiber protein kuti irege kuderedzwa ne plasmin uye kupera, pakupedzisira inowana hemostasis. Inoshandiswa mukurapa kweacute kana isingaperi, yemuno kana systemic primary fiber fibrinolytic hyperthyroidism inokonzerwa nekubuda ropa, senge obstetric hemorrhage, renal hemorrhage, hemorrhage ye hypertrophy ye prostate, hemophilia, pulmonary tuberculosis hemoptysis, kubuda mudumbu, mushure mekushanda kwechiropa, mapapu. , spleen uye zvimwe viscera kubuda ropa; zvakare inogona kushandiswa mukuvhiya kana kubuda ropa kusingaite etc..
Clinical tranexamic acid ine mhedzisiro yakanyanya kune chirwere chekurumwa netumbuyu, dermatitis uye eczema, simple purpura, chronic urticaria, artificial sex urticaria, chepfu kuputika uye kuputika. Uye zvakare ine imwe mhedzisiro pane erythroderma, scleroderma, systemic lupus erythematosus (SLE), Erythema multiforme, shingles uye alopecia areata. Kurapa kwenhaka angioedema mhedzisiro yakanaka zvakare. Mukurapa kweChloasma, mushonga wakajairika unoshanda anenge mavhiki matatu, akajeka anoshanda mavhiki mashanu, kosi yemazuva makumi matanhatu. Inopiwa nemuromo muhuwandu hwe 0.25 ~ 0.5 g, zuva 3 ~ 4 nguva. Varwere vashoma vanogona kusvotwa, kuneta, pruritus, kusagadzikana mudumbu, uye manyoka mhedzisiro mushure mekusiya zviratidzo zvanyangarika.
Zviratidzo
Kubuda ropa kwakasiyana-siyana kunokonzerwa neacute kana kusingaperi, localized kana systemic primary hyperfibrinolysis; yechipiri hyperfibrinolytic mamiriro anokonzerwa nekuparadzira intravascular coagulation. Kazhinji usashandise chigadzirwa ichi pamberi peheparinization.
Kushungurudzika kana kuvhiyiwa kubuda ropa munyama uye nhengo dzine akawanda plasminogen activators akadai seprostate, urethra, mapapu, uropi, chibereko, adrenal glands, uye thyroid.
Anopikisa wetishu plasminogen activator (t-PA), streptokinase, uye urokinase.
Fibrinolytic hemorrhage inokonzerwa nekubvisa pamuviri, kutanga kwekutanga placenta, kuberekwa uye amniotic fluid embolism; uye yakawedzera menorrhagia inokonzerwa ne pathological intrauterine fibrinolysis.
Cerebral neuropathy kubuda ropa zvishoma, senge subbarachnoid hemorrhage uye intracranial aneurysm hemorrhage, mhedzisiro yeAmstat mumamiriro ezvinhu aya iri nani pane yemamwe anti-fibrinolytic agents. Kunyanya kukoshesa kunofanira kubhadharwa kune ngozi yecerebral edema kana cerebral infarction.Kune varwere vakaoma vane zviratidzo zvekuvhiya, chigadzirwa ichi chinogona kushandiswa chete semushonga wemishonga.
Nekurapa kwenhaka angioneurotic edema, inogona kuderedza nhamba uye kuoma kwezvikamu.
Inoshandiswa kune varwere vane hemophilia kune yavo inoshanda kubuda ropa pamwe chete nemamwe mushonga.
Varwere veHemophilia vane factor VIII kana kuti factor IX kushomeka mukubvisa zino ravo kana kuvhiyiwa nemuromo kana vachibuda ropa.
