Tsanangudzo Pfupi
Nhamba yeCAS: 1264-72-8
Molecular formula:2(C52H98N16O13).5(H2SO4)
molecular uremu: 2801.27
Kemikari chimiro:
| Basic Information | |
| Product name | Colistin sulfate |
| Giredhi | Feed Grade |
| Chitarisiko | Ichena kana inenge yakachena, hygroscopic poda |
| Assay | 99% |
| Sherufu hupenyu | 2 years |
| Packing | 20kg/katoni 20kg/drum |
| Condition | Chengetedza pa -20 ℃ kwegore rimwe (Upfu) |
Tsanangudzo yechigadzirwa
Colistin ndeye cyclic cationic decapeptide yakabatana nemafuta acid parutivi cheni, ndeyeboka rezvakafanana zvakarongeka mabhakitiriya antimicrobial peptides.Colistin sulfate mushonga unorwisa mabhakitiriya wepolypeptide unodzivirira giremu-negative bhakitiriya nekusunga kune lipopolysaccharides uye phospholipids mukunze kwesero membrane ye gram-negative bacteria.
Colistin sulfate, inozivikanwawo se colistin sulfate, Christian (Colistin), Polymyxin E (Polymyxin E), antiphytin, chena kana ingangoita chena poda, isina kunhuhwirira, inovava kunyorova, inonyungudika mumvura, inonyungudika zvishoma mumethanol, ethanol, inenge isinganyunguriki. acetone, ether, alkali yemahara inonyungudika zvishoma mumvura.Yakagadzikana muPH3-7.5 renji.Mycolistin sulfate inogadzirwa neBacillus polymyxoides, ine yakasimba antibacterial effect pa gram-negative bacteria.Inoshandiswa kurapa zvirwere zvemukati zvinokonzerwa ne gram-negative bacteria, uye inoshandiswa sekuwedzera kwekudya nekukura kuri pachena kusimudzira maitiro.Iko kusanganiswa kwe sulfadiazine effect kuri nani.
Basa rechigadzirwa
Colistin sulfate granules yakagadziridzwa mukugadzikana kwe potency mukudyisa uye kuratidza kunyungudika kwakanyanya kunyangwe ichigadzirwa pasina kushandisa chero inodhura inotakura kana midziyo yakakosha.Kunyanya, colistin sulfate granules inosanganisira colistin sulfate uye ine particle madhayamita e150 kusvika 1500m, nzvimbo chaiyo ye40 kusvika 500 cm2/g, nguva yekunyorova yemaminetsi mashanu kana pasi uye mwando wegumi muzana kana pasi.
Pharmacodynamics
Colistin inonzi polymyxin antibiotic agent.Polymyxins ndeye cationic polypeptides iyo inovhiringidza bhakitiriya sero membrane kuburikidza nedetergent semeshini.Nekuvandudzwa kwemishonga ine chepfu shoma, yakadai seyakawedzerwa-spectrum penicillins uye cephalosporins, parenteral polymyxin kushandiswa kwakasiiwa zvakanyanya, kunze kwekurapwa kwezvirwere zvepulmonary zvisingaite muvarwere vane cystic fibrosis.
